Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

Myofibroblasts produce the fibrous scar in hepatic fibrosis. In the carbon tetrachloride (CCl(4)) model of liver fibrosis, quiescent hepatic stellate cells (HSC) are activated to become myofibroblasts. When the underlying etiological agent is removed, clinical and experimental fibrosis undergoes a r...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Tatiana Kisseleva, Min Cong, Yong‐Han Paik, David Scholten, Chunyan Jiang, Christopher Benner, Keiko Iwaisako, Thomas Moore‐Morris, Brian T. Scott, Hidekazu Tsukamoto, Sylvia Μ. Evans, Wolfgang Dillmann, Christopher K. Glass, David A. Brenner
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2012
Rochtain ar líne:https://doi.org/10.1073/pnas.1201840109
https://www.pnas.org/content/pnas/109/24/9448.full.pdf
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