Calcineurin-Inhibitor-Free Immunosuppression Based on the JAK Inhibitor CP-690,550: A Pilot Study in De Novo Kidney Allograft Recipients

Calcineurin-Inhibitor-Free Immunosuppression Based on the JAK Inhibitor CP-690,550: A Pilot Study in De Novo Kidney Allograft Recipients

This randomized, pilot study compared the Janus kinase inhibitor CP-690,550 (15 mg BID [CP15] and 30 mg BID [CP30], n = 20 each) with tacrolimus (n = 21) in de novo kidney allograft recipients. Patients received an IL-2 receptor antagonist, concomitant mycophenolate mofetil (MMF) and corticosteroids...

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Main Authors: Stéphan Busque, Joseph R. Leventhal, Daniel C. Brennan, Steven Steinberg, Göran B. Klintmalm, T. Shah, S. Mulgaonkar, Jonathan S. Bromberg, F. Vincenti, Sundaram Hariharan, Douglas P. Slakey, V.R. Peddi, Rosemary A. Fisher, Nervin Lawendy, C. Wang, Gordon Chun‐Kau Chan
格式: Artigo
語言:英语
出版: 2009
在線閱讀:https://doi.org/10.1111/j.1600-6143.2009.02720.x
http://www.amjtransplant.org/article/S1600613522271184/pdf
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https://doi.org/10.1111/j.1600-6143.2009.02720.x
http://www.amjtransplant.org/article/S1600613522271184/pdf

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