Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge

Nizatidine (NIZ), closely related to Cimetidine, is a histamine H2 receptor inverse agonist used primarily as an anti-acid drug. Recent studies showed that this class of compounds may also modulate immune responses. To evaluate adjuvant effects of NIZ on vaccine immune modulation, we formulated NIZ...

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Hlavní autoři: Shuang Wang, Bing Wu, Jia Xue, Ming Wang, Ruiai Chen, Bin Wang
Médium: Artigo
Jazyk:angličtina
Vydáno: 2013
On-line přístup:https://doi.org/10.4161/hv.27165
https://www.tandfonline.com/doi/pdf/10.4161/hv.27165?needAccess=true
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