Genetic ablation of retinal pigment epithelial cells reveals the adaptive response of the epithelium and impact on photoreceptors

The retinal pigment epithelium (RPE) plays a critical role in the maintenance of the outer retina. RPE cell death or dysfunction drives the pathophysiology of many retinal diseases, but the physiological response of the retina to RPE cell loss is poorly understood, mainly because of the absence of s...

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Bibliographic Details
Main Authors: Rebecca Longbottom, Marcus Fruttiger, R.H. Douglas, Juan Pedro Martı́nez-Barberá, John Greenwood, Stephen E. Moss
Format: Artigo
Language:English
Published: 2009
Online Access:https://doi.org/10.1073/pnas.0902593106
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