Fatty acids are required for epidermal permeability barrier function.
The permeability barrier is mediated by a mixture of ceramides, sterols, and free fatty acids arranged as extracellular lamellar bilayers in the stratum corneum. Whereas prior studies have shown that cholesterol and ceramides are required for normal barrier function, definitive evidence for the impo...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
1993
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| 在线阅读: | https://doi.org/10.1172/jci116652 http://www.jci.org/articles/view/116652/files/pdf |
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