The emerging roles of ARID1A in tumor suppression
ARID1A has emerged as a tumor suppressor gene, which is mutated in a broad spectrum of cancers, especially in those arising from ectopic or eutopic endometrium. As a subunit of SWI/SNF chromatin remodeler, ARID1A facilitates target-specific binding of SWI/SNF complexes to chromatin, thereby altering...
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| Main Authors: | , , |
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| Format: | Revisão |
| Language: | English |
| Published: |
2014
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| Online Access: | https://doi.org/10.4161/cbt.28411 https://www.tandfonline.com/doi/pdf/10.4161/cbt.28411?needAccess=true |
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