An RNA Aptamer That Specifically Binds to the Glycosylated Hemagglutinin of Avian Influenza Virus and Suppresses Viral Infection in Cells
The influenza virus surface glycoprotein hemagglutinin (HA) is responsible for viral attachment to sialic acid-containing host cell receptors and it facilitates the initial stage of viral infection. In the present study, we isolated an RNA aptamer specific to the glycosylated receptor-binding domain...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2014
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| 在线阅读: | https://doi.org/10.1371/journal.pone.0097574 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0097574&type=printable |
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