An RNA Aptamer That Specifically Binds to the Glycosylated Hemagglutinin of Avian Influenza Virus and Suppresses Viral Infection in Cells

The influenza virus surface glycoprotein hemagglutinin (HA) is responsible for viral attachment to sialic acid-containing host cell receptors and it facilitates the initial stage of viral infection. In the present study, we isolated an RNA aptamer specific to the glycosylated receptor-binding domain...

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Autors principals: Hyun‐Mi Kwon, Kwang Hyun Lee, Byung Woo Han, Mi Ra Han, Dong Ho Kim, Dong‐Eun Kim
Format: Artigo
Idioma:anglès
Publicat: 2014
Accés en línia:https://doi.org/10.1371/journal.pone.0097574
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0097574&type=printable
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