Angiopoietin-1 Opposes VEGF-Induced Increase in Endothelial Permeability by Inhibiting TRPC1-Dependent Ca <sup>2</sup> Influx

Angiopoietin-1 (Ang1) exerts a vascular endothelial barrier protective effect by blocking the action of permeability-increasing mediators such as vascular endothelial growth factor (VEGF) through unclear mechanisms. Because VEGF may signal endothelial hyperpermeability through the phospholipase C (P...

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Main Authors: David H. Jho, Dolly Mehta, Gias U. Ahmmed, Xiao-Pei Gao, Chinnaswamy Tiruppathì, Michael Broman, Asrar B. Malik
格式: Artigo
语言:英语
出版: 2005
在线阅读:https://doi.org/10.1161/01.res.0000171894.03801.03
https://www.ahajournals.org/doi/pdf/10.1161/01.RES.0000171894.03801.03
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