Genome-wide identification of conserved regulatory function in diverged sequences

Plasticity of gene regulatory encryption can permit DNA sequence divergence without loss of function. Functional information is preserved through conservation of the composition of transcription factor binding sites (TFBS) in a regulatory element. We have developed a method that can accurately ident...

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Hlavní autoři: Leila Taher, David McGaughey, Samantha Maragh, Ivy Aneas, Seneca L. Bessling, Webb Miller, Marcelo A. Nóbrega, Andrew S. McCallion, Ivan Ovcharenko
Médium: Artigo
Jazyk:angličtina
Vydáno: 2011
On-line přístup:https://doi.org/10.1101/gr.119016.110
https://genome.cshlp.org/content/21/7/1139.full.pdf
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