Genome-wide identification of conserved regulatory function in diverged sequences
Plasticity of gene regulatory encryption can permit DNA sequence divergence without loss of function. Functional information is preserved through conservation of the composition of transcription factor binding sites (TFBS) in a regulatory element. We have developed a method that can accurately ident...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2011
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| 在线阅读: | https://doi.org/10.1101/gr.119016.110 https://genome.cshlp.org/content/21/7/1139.full.pdf |
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