The Aspergillus fumigatus Protein GliK Protects against Oxidative Stress and Is Essential for Gliotoxin Biosynthesis

ABSTRACT The function of a number of genes in the gliotoxin biosynthetic cluster ( gli ) in Aspergillus fumigatus remains unknown. Here, we demonstrate that gliK deletion from two strains of A. fumigatus completely abolished gliotoxin biosynthesis. Furthermore, exogenous H 2 O 2 (1 mM), but not glio...

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Hlavní autoři: Lorna Gallagher, Rebecca A. Owens, Stephen K. Dolan, Grainne O’Keeffe, Markus Schrettl, Kevin Kavanagh, Gary W. Jones, Seán Doyle
Médium: Artigo
Jazyk:angličtina
Vydáno: 2012
On-line přístup:https://doi.org/10.1128/ec.00113-12
https://ec.asm.org/content/eukcell/11/10/1226.full.pdf
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