Weighting in sequence space: a comparison of methods in terms of generalized sequences.

Four methods for weighting aligned biological sequences have recently appeared that differ mathematically, philosophically, and in their results. Thus, while there is consensus about the need to weight sequences, the method to use is contentious. A geometric analysis based on a continuous sequence s...

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Detalhes bibliográficos
Main Authors: Martin Vingron, Peter R. Sibbald
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Acesso em linha:https://doi.org/10.1073/pnas.90.19.8777
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