Cerebellar ataxia and Purkinje cell dysfunction caused by Ca <sup>2+</sup> -activated K <sup>+</sup> channel deficiency

Cerebellar ataxia and Purkinje cell dysfunction caused by Ca <sup>2+</sup> -activated K <sup>+</sup> channel deficiency

Malfunctions of potassium channels are increasingly implicated as causes of neurological disorders. However, the functional roles of the large-conductance voltage- and Ca(2+)-activated K(+) channel (BK channel), a unique calcium, and voltage-activated potassium channel type have remained elusive. He...

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Main Authors: Matthias Sausbier, Hua Hu, Claudia Arntz, Susanne Feil, S. Kamm, Helmuth Adelsberger, Ulrike Sausbier, Claudia A. Sailer, Robert Feil, Franz Hofmann, Michael Korth, Michael J. Shipston, H G Knaus, David P Wolfer, Christine M. Pedroarena, Johan F. Storm, Peter Ruth
Format: Artigo
Language:English
Published: 2004
Online Access:https://doi.org/10.1073/pnas.0401702101
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https://doi.org/10.1073/pnas.0401702101

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