NRAGE, a p75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death through a JNK-dependent Mitochondrial Pathway
The p75 neurotrophin receptor (p75NTR) mediates signaling events leading to activation of the JNK pathway and cell death in a variety of cell types. We recently identified NRAGE, a protein that directly interacts with the p75NTR cytosolic region and facilitates p75NTR-mediated cell death. For the pr...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2002
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| Online Access: | https://doi.org/10.1074/jbc.m205324200 http://www.jbc.org/article/S002192581933025X/pdf |
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