Overexpression of a calcium-binding protein, S100 beta, in astrocytes alters synaptic plasticity and impairs spatial learning in transgenic mice.
Recent evidence suggests that slowly propagating Ca2+ waves from astrocytes can modulate the function of neurons. Altering astrocytic calcium processes in vivo may therefore affect neuronal and behavioral phenotypes. Previously, we generated transgenic mice that overexpress an astrocytic calcium-bin...
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Hlavní autoři: | , , , |
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Médium: | Artigo |
Jazyk: | angličtina |
Vydáno: |
1995
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On-line přístup: | https://doi.org/10.1101/lm.2.1.26 http://learnmem.cshlp.org/content/2/1/26.full.pdf |
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