Anaerobic NADH-Fumarate Reductase System Is Predominant in the Respiratory Chain of <i>Echinococcus multilocularis</i> , Providing a Novel Target for the Chemotherapy of Alveolar Echinococcosis

ABSTRACT Alveolar echinococcosis, which is due to the massive growth of larval Echinococcus multilocularis , is a life-threatening parasitic zoonosis distributed widely across the northern hemisphere. Commercially available chemotherapeutic compounds have parasitostatic but not parasitocidal effects...

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Main Authors: Jun Matsumoto, Kimitoshi Sakamoto, Noriko Shinjyo, Yasutoshi Kido, Nao Yamamoto, Kinpei Yagi, Hideto Miyoshi, Nariaki Nonaka, Ken Katakura, Kiyoshi Kita, Yuzaburo Oku
Format: Artigo
Language:English
Published: 2007
Online Access:https://doi.org/10.1128/aac.00378-07
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