Identification of Evolutionarily Conserved Exons as Regulated Targets for the Splicing Activator Tra2β in Development
Alternative splicing amplifies the information content of the genome, creating multiple mRNA isoforms from single genes. The evolutionarily conserved splicing activator Tra2β (Sfrs10) is essential for mouse embryogenesis and implicated in spermatogenesis. Here we find that Tra2β is up-regulated as t...
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Main Authors: | , , , , , , , , , , , , , , , |
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格式: | Artigo |
語言: | 英语 |
出版: |
2011
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在線閱讀: | https://doi.org/10.1371/journal.pgen.1002390 https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002390&type=printable |
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