Identification of Evolutionarily Conserved Exons as Regulated Targets for the Splicing Activator Tra2β in Development

Identification of Evolutionarily Conserved Exons as Regulated Targets for the Splicing Activator Tra2β in Development

Alternative splicing amplifies the information content of the genome, creating multiple mRNA isoforms from single genes. The evolutionarily conserved splicing activator Tra2β (Sfrs10) is essential for mouse embryogenesis and implicated in spermatogenesis. Here we find that Tra2β is up-regulated as t...

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Hlavní autoři: Sushma Nagaraja Grellscheid, Caroline Dalgliesh, Markus Storbeck, Andrew Best, Yilei Liu, Miriam Jakubik, Ylva Mende, Ingrid Ehrmann, Tomaž Curk, Kristina Roßbach, Cyril F. Bourgeois, James Stévenin, D. Grellscheid, Michael S. Jackson, Brunhilde Wirth, David J. Elliott
Médium: Artigo
Jazyk:angličtina
Vydáno: 2011
On-line přístup:https://doi.org/10.1371/journal.pgen.1002390
https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002390&type=printable
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https://doi.org/10.1371/journal.pgen.1002390
https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002390&type=printable

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