Overlapping and distinct role of CXCR7‐SDF‐1/ITAC and CXCR4‐SDF‐1 axes in regulating metastatic behavior of human rhabdomyosarcomas

Abstract We have demonstrated that the α‐chemokine stromal‐derived factor (SDF)‐1‐CXCR4 axis plays an important role in rhabdomyosarcoma (RMS) metastasis. With the recent description of CXCR7, a new receptor for SDF‐1 that also binds the interferon‐inducible T‐cell α chemoattractant (ITAC) chemokine...

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Main Authors: Katarzyna Grymuła, Maciej Tarnowski, Marcin Wysoczynski, Justyna Drukała, Frederic G. Barr, Janina Ratajczak, Magda Kucia, Mariusz Z. Ratajczak
Format: Artigo
Language:English
Published: 2010
Online Access:https://doi.org/10.1002/ijc.25245
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.25245
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