Analysis of Complement Expression in Light-Induced Retinal Degeneration: Synthesis and Deposition of C3 by Microglia/Macrophages Is Associated with Focal Photoreceptor Degeneration
Purpose.: To investigate the expression and localization of complement system mRNA and protein in a light-induced model of progressive retinal degeneration. Methods.: Sprague-Dawley (SD) rats were exposed to 1000 lux of bright continuous light (BCL) for up to 24 hours. At time points during (1–24 ho...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2011
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| Online Access: | https://doi.org/10.1167/iovs.10-7119 |
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