Tetramethylpyrazine Produces Antidepressant-Like Effects in Mice Through Promotion of BDNF Signaling Pathway

Background:Current antidepressants are clinically effective only after several weeks of administration. Tetramethylpyrazine (TMP) is an identified component of Ligusticum wallichii with neuroprotective effects. Here, we investigated the antidepressant effects of TMP in mice models of depression.

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Bibliografische gegevens
Hoofdauteurs: Bo Jiang, Chao Huang, Xiangfan Chen, Lijuan Tong, Wei Zhang
Formaat: Artigo
Taal:Engels
Gepubliceerd in: 2015
Online toegang:https://doi.org/10.1093/ijnp/pyv010
https://academic.oup.com/ijnp/article-pdf/18/8/pyv010/14095148/pyv010.pdf
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