Dynamic Patterns of Histone Methylation Are Associated with Ontogenic Expression of the <i>Cyp3a</i> Genes during Mouse Liver Maturation

Human cytochrome P450 3A (CYP3A) members are major drug-metabolizing enzymes in the liver. Two genes, <i>CYP3A4</i> and <i>CYP3A7</i>, exhibit a developmental switch in gene expression during liver maturation. <i>CYP3A4</i> is mainly expressed in adults, whereas &...

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Príomhchruthaitheoirí: Ye Li, Yue Cui, Steven N. Hart, Curtis D. Klaassen, Xiao Zhong
Formáid: Artigo
Teanga:Béarla
Foilsithe / Cruthaithe: 2009
Rochtain ar líne:https://doi.org/10.1124/mol.108.052993
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