Apoptosis Signal-Regulating Kinase 1 in Amyloid β Peptide-Induced Cerebral Endothelial Cell Apoptosis

A pathological hallmark of Alzheimer's disease is accumulation of amyloid-beta peptide (Abeta) in senile plaques. Abeta has also been implicated in vascular degeneration in cerebral amyloid angiopathy because of its cytotoxic effects on non-neuronal cells, including cerebral endothelial cells (...

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Main Authors: Ming‐Jen Hsu, Chung Y. Hsu, Bing-Chang Chen, Mei-Chieh Chen, George Ou, Chien‐Huang Lin
格式: Artigo
语言:英语
出版: 2007
在线阅读:https://doi.org/10.1523/jneurosci.1874-06.2007
https://www.jneurosci.org/content/jneuro/27/21/5719.full.pdf
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