<scp>GAP</scp>161 targets and downregulates <scp>G</scp>3<scp>BP</scp> to suppress cell growth and potentiate cisplaitin‐mediated cytotoxicity to colon carcinoma <scp>HCT</scp>116 cells
Ras-GTPase-activating protein SH3 domain-binding proteins (G3BP) are overexpressed in various human tumors and participate in several signaling pathways involved in growth, differentiation and apoptosis. G3BP interact with RasGAP (Ras-GTPase activating protein) only in growing cells and depend on Ra...
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| Main Authors: | , , , , , |
|---|---|
| Format: | Artigo |
| Language: | English |
| Published: |
2012
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| Online Access: | https://doi.org/10.1111/j.1349-7006.2012.02361.x https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1349-7006.2012.02361.x |
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