Decreased sickle red blood cell adhesion to laminin by hydroxyurea is associated with inhibition of Lu/BCAM protein phosphorylation

Míreanna comhchosúla

• Aggregation of mononuclear and red blood cells through an α(4)β(1)-Lu/basal cell adhesion molecule interaction in sickle cell disease
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  Foilsithe / Cruthaithe: (2010)
• Hydroxycarbamide Decreases Sickle Reticulocyte Adhesion to Resting Endothelium by Inhibiting Endothelial Lutheran/Basal Cell Adhesion Molecule (Lu/BCAM) through Phosphodiesterase 4A Activation
  de réir: Chaar, Vicky, et al.
  Foilsithe / Cruthaithe: (2014)
• Increased adhesion to endothelial cells of erythrocytes from patients with polycythemia vera is mediated by laminin α5 chain and Lu/BCAM
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• Population pharmacokinetics and pharmacodynamics of hydroxyurea in sickle cell anemia patients, a basis for optimizing the dosing regimen
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  Foilsithe / Cruthaithe: (2011)
• Biological parameters predictive of percent dense red blood cell decrease under hydroxyurea
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  Foilsithe / Cruthaithe: (2015)