Enhanced Detection of Human Immunodeficiency Virus Type 1-Specific T-Cell Responses to Highly Variable Regions by Using Peptides Based on Autologous Virus Sequences
The antigenic diversity of human immunodeficiency virus type 1 (HIV-1) represents a significant challenge for vaccine design as well as the comprehensive assessment of HIV-1-specific immune responses in infected persons. In this study we assessed the impact of antigen variability on the characteriza...
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Main Authors: | , , , , , , , , , , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2003
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在线阅读: | https://doi.org/10.1128/jvi.77.13.7330-7340.2003 |
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