Enhanced Detection of Human Immunodeficiency Virus Type 1-Specific T-Cell Responses to Highly Variable Regions by Using Peptides Based on Autologous Virus Sequences

Enhanced Detection of Human Immunodeficiency Virus Type 1-Specific T-Cell Responses to Highly Variable Regions by Using Peptides Based on Autologous Virus Sequences

The antigenic diversity of human immunodeficiency virus type 1 (HIV-1) represents a significant challenge for vaccine design as well as the comprehensive assessment of HIV-1-specific immune responses in infected persons. In this study we assessed the impact of antigen variability on the characteriza...

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Hlavní autoři: Marcus Altfeld, Marylyn M. Addo, Raj Shankarappa, Paul K. Lee, Todd M. Allen, Xu G. Yu, Almas Rathod, Jason Harlow, Kristin O’Sullivan, Mary N. Johnston, Philip Goulder, James I. Mullins, Eric Rosenberg, Christian Brander, Bette Korber, Bruce D. Walker
Médium: Artigo
Jazyk:angličtina
Vydáno: 2003
On-line přístup:https://doi.org/10.1128/jvi.77.13.7330-7340.2003
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https://doi.org/10.1128/jvi.77.13.7330-7340.2003

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