Hereditary diffuse gastric cancer: association with lobular breast cancer
Hereditary diffuse gastric cancer (HDGC) has been shown to be caused by germline mutations in the gene CDH1 located at 16q22.1, which encodes the cell-cell adhesion molecule, E-cadherin. Not only does loss of expression of E-cadherin account for the morphologic differences between intestinal and dif...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Revisão |
| Язык: | английский |
| Опубликовано: |
2007
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| Online-ссылка: | https://doi.org/10.1007/s10689-007-9172-6 https://link.springer.com/content/pdf/10.1007/s10689-007-9172-6.pdf |
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