Loss of heterozygosity analysis at the <i>BRCA</i> loci in tumor samples from patients with familial breast cancer
The BRCA1 and BRCA2 genes are responsible for a high proportion of familial breast cancer; germline mutations in these genes confer a lifetime risk of about 70% for developing breast cancer. Most of the described deleterious mutations are small deletions or insertions that originate a truncated prot...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 语言: | 英语 |
| 出版: |
2002
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| 在线阅读: | https://doi.org/10.1002/ijc.10337 https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.10337 |
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