Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons

Members of the Kv7 family (Kv7.2–Kv7.5) generate a subthreshold K + current, the M− current. This regulates the excitability of many peripheral and central neurons. Recent evidence shows that Kv7.2 and Kv7.3 subunits are targeted to the axon initial segment of hippocampal neurons by association with...

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Auteurs principaux: Mala M. Shah, Michele Migliore, Ignacio Leyva-Valencia, Edward C. Cooper, David A. Brown
Format: Artigo
Langue:anglais
Publié: 2008
Accès en ligne:https://doi.org/10.1073/pnas.0802805105
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