Attenuation of TNFSF10/TRAIL-induced apoptosis by an autophagic survival pathway involving TRAF2- and RIPK1/RIP1-mediated MAPK8/JNK activation
Although it is known that tumor necrosis factor-related apoptosis-inducing ligand (TNFSF10/TRAIL) induces autophagy, the mechanism by which autophagy is activated by TNFSF10 is still elusive. In this report, we show evidence that TRAF2- and RIPK1-mediated MAPK8/JNK activation is required for TNFSF10...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | inglés |
| Publicado: |
2012
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| Acceso en liña: | https://doi.org/10.4161/auto.22145 https://www.tandfonline.com/doi/pdf/10.4161/auto.22145?needAccess=true |
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