Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors.

Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors.

Sodium-dependent uptake of bile acids across the hepatic basolateral membrane is rapidly and profoundly diminished during sepsis, thus contributing to the pathogenesis of sepsis-associated cholestasis. This effect is mediated by endotoxin or effector cytokines, which reduce expression of several hep...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Michael Trauner, Marco Arrese, Hyunjung Lee, James L. Boyer, Saul J. Karpen
Formáid:	Artigo
Teanga:	Béarla
Foilsithe / Cruthaithe:	1998
Rochtain ar líne:	https://doi.org/10.1172/jci1680 http://www.jci.org/articles/view/1680/files/pdf
Clibeanna:	Cuir clib leis Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!

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