A functional screen identifies miRNAs that inhibit DNA repair and sensitize prostate cancer cells to ionizing radiation
MicroRNAs (miRNAs) have been implicated in DNA repair pathways through transcriptional responses to DNA damaging agents or through predicted miRNA regulation of DNA repair genes. We hypothesized that additional DNA damage regulating miRNAs could be identified by screening a library of 810 miRNA mime...
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| Main Authors: | , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | 英语 |
| 出版: |
2015
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| 在線閱讀: | https://doi.org/10.1093/nar/gkv273 https://academic.oup.com/nar/article-pdf/43/8/4075/17437262/gkv273.pdf |
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