A functional screen identifies miRNAs that inhibit DNA repair and sensitize prostate cancer cells to ionizing radiation

A functional screen identifies miRNAs that inhibit DNA repair and sensitize prostate cancer cells to ionizing radiation

MicroRNAs (miRNAs) have been implicated in DNA repair pathways through transcriptional responses to DNA damaging agents or through predicted miRNA regulation of DNA repair genes. We hypothesized that additional DNA damage regulating miRNAs could be identified by screening a library of 810 miRNA mime...

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Hauptverfasser: Koji Hatano, Binod Kumar, Yonggang Zhang, Jonathan B. Coulter, Mohammad Hedayati, Brian M. Mears, Xiaohua Ni, Tarana A. Kudrolli, Wasim H. Chowdhury, Ronald Rodríguez, Theodore L. DeWeese, Shawn E. Lupold
Format: Artigo
Sprache:Englisch
Veröffentlicht: 2015
Online-Zugang:https://doi.org/10.1093/nar/gkv273
https://academic.oup.com/nar/article-pdf/43/8/4075/17437262/gkv273.pdf
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https://doi.org/10.1093/nar/gkv273
https://academic.oup.com/nar/article-pdf/43/8/4075/17437262/gkv273.pdf

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