Type I interferons suppress CD4<sup>+</sup> T‐cell‐dependent parasite control during blood‐stage <i>Plasmodium</i> infection

Type I interferons suppress CD4<sup>+</sup> T‐cell‐dependent parasite control during blood‐stage <i>Plasmodium</i> infection

Abstract During blood‐stage Plasmodium infection, large‐scale invasion of RBCs often occurs before the generation of cellular immune responses. In Plasmodium berghei ANKA (PbA)‐infected C57BL/6 mice, CD4 + T cells controlled parasite numbers poorly, instead providing early help to pathogenic CD8 + T...

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Main Authors: Ashraful Haque, Shannon E. Best, Anne Ammerdorffer, Laure Desbarrieres, Marcela Montes de, Fiona H. Amante, Fabian de Labastida Rivera, Paul J. Hertzog, Glen M. Boyle, Geoffrey R. Hill, Christian Engwerda
Format: Artigo
Language:English
Published: 2011
Online Access:https://doi.org/10.1002/eji.201141539
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eji.201141539
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https://doi.org/10.1002/eji.201141539
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eji.201141539

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