Pluripotency Associated Genes Are Reactivated by Chromatin-Modifying Agents in Neurosphere Cells
Abstract Chromatin architecture in stem cells determines the pattern of gene expression and thereby cell identity and fate. The chromatin-modifying agents trichostatin A (TSA) and 5-Aza-2′-deoxycytidine (AzaC) affect histone acetylation and DNA methylation, respectively, and thereby influence chroma...
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Main Authors: | , , , , , , , , , |
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格式: | Artigo |
语言: | 英语 |
出版: |
2008
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在线阅读: | https://doi.org/10.1634/stemcells.2007-0649 https://academic.oup.com/stmcls/article-pdf/26/4/920/41943032/stmcls_26_4_920.pdf |
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