Pluripotency Associated Genes Are Reactivated by Chromatin-Modifying Agents in Neurosphere Cells

Abstract Chromatin architecture in stem cells determines the pattern of gene expression and thereby cell identity and fate. The chromatin-modifying agents trichostatin A (TSA) and 5-Aza-2′-deoxycytidine (AzaC) affect histone acetylation and DNA methylation, respectively, and thereby influence chroma...

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Main Authors: David Ruau, Roberto Enseñat‐Waser, Timo C. Dinger, Duttu S. Vallabhapurapu, Alexandra Rolletschek, Christine Hacker, Thomas Hieronymus, Anna M. Wobus, Albrecht Müller, Martin Zenke
格式: Artigo
语言:英语
出版: 2008
在线阅读:https://doi.org/10.1634/stemcells.2007-0649
https://academic.oup.com/stmcls/article-pdf/26/4/920/41943032/stmcls_26_4_920.pdf
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