Digital PCR Validates 8q Dosage as Prognostic Tool in Uveal Melanoma
Background Uveal melanoma (UM) development and progression is correlated with specific molecular changes. Recurrent mutations in GNAQ and GNA11 initiate UM development while tumour progression is correlated with monosomy of chromosome 3 and gain of chromosome 8q. Hence, molecular analysis of UM is u...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2015
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| Online Access: | https://doi.org/10.1371/journal.pone.0116371 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0116371&type=printable |
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