SnugDock: Paratope Structural Optimization during Antibody-Antigen Docking Compensates for Errors in Antibody Homology Models

High resolution structures of antibody-antigen complexes are useful for analyzing the binding interface and to make rational choices for antibody engineering. When a crystallographic structure of a complex is unavailable, the structure must be predicted using computational tools. In this work, we il...

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Bibliographic Details
Main Authors: Aroop Sircar, Jeffrey J. Gray
Format: Artigo
Language:English
Published: 2010
Online Access:https://doi.org/10.1371/journal.pcbi.1000644
https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000644&type=printable
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