SnugDock: Paratope Structural Optimization during Antibody-Antigen Docking Compensates for Errors in Antibody Homology Models
High resolution structures of antibody-antigen complexes are useful for analyzing the binding interface and to make rational choices for antibody engineering. When a crystallographic structure of a complex is unavailable, the structure must be predicted using computational tools. In this work, we il...
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Main Authors: | , |
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Format: | Artigo |
Language: | English |
Published: |
2010
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Online Access: | https://doi.org/10.1371/journal.pcbi.1000644 https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000644&type=printable |
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