Defining the pathogenic role of telomerase mutations in myelodysplastic syndrome and acute myeloid leukemia

Defining the pathogenic role of telomerase mutations in myelodysplastic syndrome and acute myeloid leukemia

The primary pathology in many cases of myelodysplasia (MDS) and acute myeloid leukemia (AML) remains unknown. In some cases, two or more affected members have been identified in the same family. To date, mutations in two genes have been directly implicated: the hematopoietic transcription factors RU...

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Autores principales: Michael Kirwan, Tom Vulliamy, Anna Marrone, Amanda J. Walne, Richard Beswick, Peter Hillmen, Richard J. Kelly, Andrew Stewart, David Bowen, Stefan Schönland, Annika M. Whittle, Anthony McVerry, Maria Gilleece, Inderjeet Dokal
Formato: Artigo
Lenguaje:inglés
Publicado: 2009
Acceso en línea:https://doi.org/10.1002/humu.21115
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https://doi.org/10.1002/humu.21115

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