Defining the pathogenic role of telomerase mutations in myelodysplastic syndrome and acute myeloid leukemia

Defining the pathogenic role of telomerase mutations in myelodysplastic syndrome and acute myeloid leukemia

The primary pathology in many cases of myelodysplasia (MDS) and acute myeloid leukemia (AML) remains unknown. In some cases, two or more affected members have been identified in the same family. To date, mutations in two genes have been directly implicated: the hematopoietic transcription factors RU...

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Main Authors: Michael Kirwan, Tom Vulliamy, Anna Marrone, Amanda J. Walne, Richard Beswick, Peter Hillmen, Richard J. Kelly, Andrew Stewart, David Bowen, Stefan Schönland, Annika M. Whittle, Anthony McVerry, Maria Gilleece, Inderjeet Dokal
Format: Artigo
Language:English
Published: 2009
Online Access:https://doi.org/10.1002/humu.21115
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https://doi.org/10.1002/humu.21115

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