Dual interaction of factor H with C3d and glycosaminoglycans in host–nonhost discrimination by complement

The alternative pathway of complement is important in innate immunity, attacking not only microbes but all unprotected biological surfaces through powerful amplification. It is unresolved how host and nonhost surfaces are distinguished at the molecular level, but key components are domains 19–20 of...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Tommi Kajander, Markus J. Lehtinen, Satu Hyvärinen, Arnab Bhattacharjee, Elisa Leung, David E. Isenman, Seppo Meri, Adrian Goldman, T. Sakari Jokiranta
Format: Artigo
Jezik:angleščina
Izdano: 2011
Online dostop:https://doi.org/10.1073/pnas.1017087108
Oznake: Označite
Brez oznak, prvi označite!