KAT6A, a Chromatin Modifier from the 8p11-p12 Amplicon is a Candidate Oncogene in Luminal Breast Cancer
The chromosome 8p11-p12 amplicon is present in 12% to 15% of breast cancers, resulting in an increase in copy number and expression of several chromatin modifiers in these tumors, including KAT6A. Previous analyses in SUM-52 breast cancer cells showed amplification and overexpression of KAT6A, and s...
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Hlavní autoři: | Brittany Turner-Ivey, Stephen T. Guest, Jonathan C. Irish, Christiana S. Kappler, Elizabeth Garrett–Mayer, Robert C. Wilson, Stephen P. Ethier |
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Médium: | Artigo |
Jazyk: | angličtina |
Vydáno: |
2014
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On-line přístup: | https://doi.org/10.1016/j.neo.2014.07.007 |
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