Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: evidence for receptor function in heterologous transfectants

Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: evidence for receptor function in heterologous transfectants

It has been recently demonstrated that the CD94/NKG2-A killer inhibitory receptor (KIR) specifically recognizes the HLA-E class Ib molecule. Moreover, the apparent CD94-mediated specific recognition of different HLA class Ia allotypes, transfected into the HLA-defective cell line 721.221, indeed dep...

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Hlavní autoři: Marta Carretero, Gabriella Palmieri, Manuel Llano, Valentino Tullio, Angela Santoni, Daniel E. Geraghty, Miguel López‐Botet
Médium: Artigo
Jazyk:angličtina
Vydáno: 1998
On-line přístup:https://doi.org/10.1002/(sici)1521-4141(199804)28:04<1280::aid-immu1280>3.0.co;2-o
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/%28SICI%291521-4141%28199804%2928%3A04%3C1280%3A%3AAID-IMMU1280%3E3.0.CO%3B2-O
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https://doi.org/10.1002/(sici)1521-4141(199804)28:04<1280::aid-immu1280>3.0.co;2-o
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/%28SICI%291521-4141%28199804%2928%3A04%3C1280%3A%3AAID-IMMU1280%3E3.0.CO%3B2-O

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