TNF‐α mediates the induction of nitric oxide synthase in macrophages but not in neutrophils in experimental cutaneous leishmaniasis

TNF‐α mediates the induction of nitric oxide synthase in macrophages but not in neutrophils in experimental cutaneous leishmaniasis

Abstract Leishmania major infection in C57BL/6 mice is controlled by the activation of a Th1 response and nitric oxide (NO) production by macrophages. TNF‐α is considered one of the most important cytokines involved in this response. In the present study, we investigated the expression of nitric oxi...

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Hlavní autoři: Simone Gonçalves Fonseca, Pedro Roosevelt Torres Romão, Florêncio Figueiredo, Ruth Helena de Morais, Hermenio Lima, Sérgio H. Ferreira, Fernando Q. Cunha
Médium: Artigo
Jazyk:angličtina
Vydáno: 2003
On-line přístup:https://doi.org/10.1002/eji.200320335
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eji.200320335
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https://doi.org/10.1002/eji.200320335
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eji.200320335

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