CHOP Potentially Co-Operates with FOXO3a in Neuronal Cells to Regulate PUMA and BIM Expression in Response to ER Stress

Endoplasmic reticulum (ER) stress-induced apoptosis has been implicated in various neurodegenerative diseases including Parkinson Disease, Alzheimer Disease and Huntington Disease. PUMA (p53 upregulated modulator of apoptosis) and BIM (BCL2 interacting mediator of cell death), pro-apoptotic BH3 doma...

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Bibliographic Details
Main Authors: Arindam Ghosh, Barbara J. Klocke, Mary E. Ballestas, Kevin A. Roth
Format: Artigo
Language:English
Published: 2012
Online Access:https://doi.org/10.1371/journal.pone.0039586
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0039586&type=printable
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