CHOP Potentially Co-Operates with FOXO3a in Neuronal Cells to Regulate PUMA and BIM Expression in Response to ER Stress
Endoplasmic reticulum (ER) stress-induced apoptosis has been implicated in various neurodegenerative diseases including Parkinson Disease, Alzheimer Disease and Huntington Disease. PUMA (p53 upregulated modulator of apoptosis) and BIM (BCL2 interacting mediator of cell death), pro-apoptotic BH3 doma...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Englisch |
| Veröffentlicht: |
2012
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| Online-Zugang: | https://doi.org/10.1371/journal.pone.0039586 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0039586&type=printable |
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