CHOP Potentially Co-Operates with FOXO3a in Neuronal Cells to Regulate PUMA and BIM Expression in Response to ER Stress

Endoplasmic reticulum (ER) stress-induced apoptosis has been implicated in various neurodegenerative diseases including Parkinson Disease, Alzheimer Disease and Huntington Disease. PUMA (p53 upregulated modulator of apoptosis) and BIM (BCL2 interacting mediator of cell death), pro-apoptotic BH3 doma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Arindam Ghosh, Barbara J. Klocke, Mary E. Ballestas, Kevin A. Roth
Fformat: Artigo
Iaith:Saesneg
Cyhoeddwyd: 2012
Mynediad Ar-lein:https://doi.org/10.1371/journal.pone.0039586
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0039586&type=printable
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