CHOP Potentially Co-Operates with FOXO3a in Neuronal Cells to Regulate PUMA and BIM Expression in Response to ER Stress

CHOP Potentially Co-Operates with FOXO3a in Neuronal Cells to Regulate PUMA and BIM Expression in Response to ER Stress

Endoplasmic reticulum (ER) stress-induced apoptosis has been implicated in various neurodegenerative diseases including Parkinson Disease, Alzheimer Disease and Huntington Disease. PUMA (p53 upregulated modulator of apoptosis) and BIM (BCL2 interacting mediator of cell death), pro-apoptotic BH3 doma...

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Главные авторы:	Arindam Ghosh, Barbara J. Klocke, Mary E. Ballestas, Kevin A. Roth
Формат:	Artigo
Язык:	английский
Опубликовано:	2012
Online-ссылка:	https://doi.org/10.1371/journal.pone.0039586 https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0039586&type=printable
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